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KMID : 0360220210620040545
Journal of the Korean Ophthalmological Society
2021 Volume.62 No. 4 p.545 ~ p.551
Rhino-orbito-cerebral Actinomycosis Infection
Park Hyung-Jun

Kim Seon-Tae
Chi Mi-Jung
Abstract
Purpose: To report a case of actinomycosis infection originating in the orbitonasal cavity that quickly invaded the cerebrum.

Case summary: A-57-year-old male with a history of right tooth extraction 7 days before the first visit presented with right eyelidswelling and pain that had developed 4 days prior to the visit and had become increasingly worse. The best-corrected visualacuity was light perception. The intraocular pressure of the patient was 37 mmHg in the right eye. Eyelid abscess, subconjunctivalhemorrhage, and severe chemosis was observed. Orbital computed tomography showed multiple air pockets and enhancingsoft tissue along the periorbital, maxillary, and ethmoid sinus. Emergent endoscopic sinus surgery, lateral canthotomy,and intravenous antifungal treatment were performed due to suspicion of mucormycosis infection. Two days after treatment, exenterationcombined with otolaryngology and neurosurgery were performed, as brain magnetic resonance imaging scans indicatedthat intraorbital lesions had invaded the dura and frontal sinus. On Day 8 of treatment, Actinomyces odontolyticus wasidentified and intravenous Ampicillin was administered. Despite systemic antibiotic treatment, the infection could not becontrolled. The patient died 28 days after treatment due to persistent intracranial hemorrhage and brain edema.

Conclusions: For patients with severe eyelid swelling with a history of tooth extraction, actinomycosis infection should beconsidered. Delays in diagnosis and treatment of this infection could lead to serious consequences.
KEYWORD
Actinomycosis, Eyelid swelling, Tooth extraction
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